Anuradha Singh Gautam, Anamika Singh and Kapila Kumar
Manav Rachna International Institute of Research and Studies, India
kapila.fet@mriu.edu.in
Date Received: September 2, 2019; Date Revised: February 7, 2020
Asia Pacific Journal of Multidisciplinary Research
Vol. 8 No.1, 27-41
February 2020
P-ISSN 2350-7756
E-ISSN 2350-8442
www.apjmr.com
ASEAN Citation Index
Analysis of therapeutic value of Tinospora cordifolia 1,383 KB 1 downloads
Anuradha Singh Gautam, Anamika Singh and Kapila Kumar Manav Rachna International...
Medicinal plants are great sources of many chemicals used in the pharma industry. Crude plant extracts are mostly used in case of herbal medicines as these extracts comprise of mixtures of different phytochemical constituents or secondary metabolites with high medicinal value. In this study, the identification and interpretation of medicinally important phytoactive compounds of Tinospora cordifolia stem is done using the Gas Chromatography Mass Spectrometry (GCMS) technique. The study mainly focuses on the determination of the phytoconstituents present in the methanolic extract of stem of Tinospora
cordifolia using GCMS. Mass spectrum of each of the phytoconstituents that occur in the methanolic extract of stem of Tinospora cordifolia was matched with NIST-14 and Willey-8 spectra libraries. A total of 82 peaks were found which corresponds to quite a high number of medicinally important phytocompounds in a plant part. It can be concluded as a result of this study that we can use Tinospora cordifolia as a plant based natural alternative for the current medicinal system. Gas Chromatography Mass Spectrometry (GCMS) analysis helps to postulate the formula and structure of phytoconstituents that can be utilized in
the drug designing process and further research would help in developing novel drugs. Some of the very important phytoactive compounds like Squalene, Eicosalone, Alpha tocopherol, Stigmasterol, isopropyl- ester, Phytol, Pentanoic acid, Propyl ester or valproic acid, and 9, Linoelaidic acid, 3, 5-dimethoxy-
acetophenone, Hexadecanoic acid, Methyl Ester, n-hexadecanoic acid, Neophytadiene, Lupeol were found to be present in the stem of Tinospora cordifolia as a result of GCMS Technique. Thus, the current study is basically focused on the evaluation of various phytoconstituents of Tinospora cordifolia justifying the
utilization of this herb to treat various diseases. These findings support the traditional usage of Tinospora cordifolia in treatment of various diseases and disorders
Keywords: Bioactive components, GCMS, Tinospora cordifolia.